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Ex vivo , ASHMI significantly and dose-dependently reduced tracheal restriction to acetylcholine, which was abolished by cyclooxygenase inhibition and prostaglandin E2 receptors, EP2/EP4 receptor blockade [105]

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Liraglutide is also positioned as a first-line anti-obesity agent for the effective prevention of obesity-related cardiovascular diseases in people with obesity [48]

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Other studies have suggested that there is no significant difference in the risk of acute pancreatitis or pancreatic cancer between the two groups when GLP-1RA is used (84, 85)

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