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Commercial Development: In August 2025, Jocasta Neuroscience raised $35 million in Series A funding to advance JN-0413, a proprietary -klotho formulation, through Phase 1 trials with IND submission planned for Q4 2026

It was marketed with a seal that indicated they were certified to contain no substances banned by the NFL and NFLPA

The US Food and Drug Administration (FDA) classified these HCG injections under pregnancy category C, which means animal studies have shown adverse effects on the fetus, and there are no controlled studies in humans

Fishers exact probability test was used to assess the number of dead and surviving rats