For these reasons, it's advisable to: Maintain the standard practice of taking levothyroxine on an empty stomach, typically 3060 minutes before breakfast [9] [15] Take levothyroxine consistently at the same time each day Have thyroid function tests (TFTs) checked 68 weeks after starting GLP-1 therapy and after significant weight loss, as your levothyroxine requirements may change Patients with hypothyroidism may also experience overlapping side effects
it's prepared per individual prescription and isn't FDA-reviewed for safety, effectiveness, or quality Compounded tirzepatide uses the same active ingredient as Mounjaro and Zepbound but carries the same compounded medication qualification - not FDA-approved as a finished drug product STEP 1 trial (NEJM): 14.9% average body weight loss at 68 weeks with semaglutide 2.4mg - this was the studied FDA-approved formulation in a controlled trial setting
5 If there are clinical concerns about aspiration risk, consider a minimally invasive gastroscopy to inspect the stomach
Kannan R, Kuhlenkamp JF, Jeandidier E, Trinh H, Ookhtens M, Kaplowitz N
