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The reduction of human RNR, which was suggested to follow mechanism (ii) 46 , therefore needs to be analyzed and monothiol mechanism (iii) should be also considered

Discovery and mechanism of action of pegvisomant

Probiotics theoretically restore beneficial bacterial species that enhance SCFA production and restore barrier integrity

However, achieving sustainable outcomes will require coordinated policies that ensure fair medicine pricing, strengthen primary healthcare systems, promote healthy lifestyles, and support large-scale public health interventions