Pharmacological therapies, including GLP-1 receptor agonists, pioglitazone, and SGLT-2i, are valuable for addressing obesity, T2DM, and cardiovascular risk
In addition, it has the ability to lower cholesterol and triacylglycerols
The new filings highlight similar patterns of use followed by serious neurological symptoms
Prescription medication requiring medical supervision Contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2 Most common adverse events are gastrointestinal (nausea, diarrhea, vomiting) Dose escalation schedule important to minimize GI side effects Efficacy and Safety of the Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide in Patients With Type 2 Diabetes (SURPASS-1): A Double-Blind, Randomised, Phase 3 Trial , published in The Lancet (Rosenstock J et al., 2021