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Activated T cells produce cytokines (IL-2, IL-1, TNF-, and others) that stimulate the production of B and T cells

an explanation may be that the generation of hydrogen peroxide by the polymorphonuclear neutrophiles might cause a decrease in the quantity of reduced glutathione, whose function is to eliminate, from the red cell, the accumulated metabolites that oxidate the sulfhydryl groups formed by the oxidative stress and therefore decreasing the protective capacity of the cell

10.3389/fphar.2024.1356112 33 ZhangM.LiuQ.MengH.DuanH.LiuX.WuJ.et al (2024a)

Glutathione converts eumelanin to pheomelanin, thus regulating the melanogenesis with or without exposure to the sun