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More recently, mGPDHs protective function was validated in vivo: in a mouse model of sepsis-induced acute lung injury, mGPDH knockdown exacerbated lung injury, vascular leakage, inflammation and oxidative damage, accompanied by elevated ferroptotic markers 100

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(2025) Mapping the effectiveness and risks of GLP-1 receptor agonists

USP20 inhibitors, including GSK2643953A, reduce obesity, improve glucose tolerance, and alleviate hepatic lipid accumulation in high-fat-diet mouse models