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Common side effects of Effexor and Effexor XR include: Abdominal pain Anxiety Constipation or diarrhea Difficulty sleeping, fatigue or unusual dreams Dizziness Dry mouth Headache High cholesterol Nausea Sexual dysfunction Sweating Tiredness Tremors Vision problems Yawning Nearly one-third of patients taking Effexor XR in clinical trials developed nausea, the most common side effect of the medication

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