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It undergoes enzymatic processing from its preproglucagon peptide precursor within intestinal L-cells, ultimately giving rise to GLP-1(1-37) and peptide variants including GLP-1(7-36)

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The obesity epidemic continues to be a major health concern, leading to various health complications and an increased risk of chronic diseases

10.1038/s42003-024-07304-0 Summary Keywords pulmonary arterial hypertension, insulin-like growth factor, insulin-like GrowthFactor binding protein, insulin-like growth factor binding protein-like, pathogenicmechanisms Citation Li N, Mo D and Dai H (2025) Insulin-like growth factor family and its impact on pulmonary arterial hypertension: a review