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To accomplish this objective, fifteen adult Wistar albino rats were randomly and equally divided into three groups for 21 days: the control group received no treatment, MSG group supplemented with MSG at a dose of 30 g/kg feed, and MSG + NSS group supplemented with MSG at the same previous dose in conjugation with NSS at a dose of 30 g/kg feed

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Although initially activated to buffer metabolic stress, the PINK1-Parkin pathway becomes suppressed under chronic overload, such as prolonged palmitate exposure, resulting in dysfunctional mitochondria, heightened oxidative stress, and activation of the NLRP3 inflammasome