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Baseline blood work before starting Before your first dose of any GLP-1 medication, get baseline blood work that includes a complete blood count, comprehensive metabolic panel, ferritin, serum iron, total iron binding capacity, zinc, vitamin D (25-OH), B12, folate, TSH, free T3, free T4, and hemoglobin A1c

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However, some people are more at risk of a vitamin B-12 deficiency, including older people, vegetarians and vegans, those with intestinal disorders, and individuals with diabetes, muscular degeneration, or Lou Gehrigs disease

[17] For tirzepatide, the onset is similarly early but the magnitude is larger