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Side Effect Overview: GLP-1s, Stimulants & Other Diet Pills GLP-1 receptor agonists such as semaglutide (Wegovy, Ozempic), orforglipron (Foundayo) and liraglutide (Saxenda), and GIP and GLP-1 receptor agonists like tirzepatide (Zepbound, Mounjaro) often cause stomach side effects like diarrhea, upset stomach (nausea or vomiting), heartburn, gas, constipation, or appetite loss, among other side effects