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Choline serves as a precursor molecule for the neurotransmitter acetylcholine and has been linked to a decreased risk of Alzheimers disease and dementia

For example, neurons co-cultured with astrocytes exhibit higher levels of glutathione compared to neurons cultured alone, demonstrating that astrocytes provide additional antioxidant defenses to neurons [104-106]

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TSCI pathogenesis is characterized by two distinct phases: the primary injury, which results in irreversible mechanical damage, and the secondary injury, driven by cellular membrane disruption, apoptotic signaling, and ischemia caused by microvascular compromise [4, 5]