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Common reasons include: Pernicious anemia , an autoimmune condition affecting intrinsic factor production Gastrointestinal disorders, such as Crohns disease or celiac disease Prolonged use of certain medications, like proton pump inhibitors Knowing these causes helps spot at-risk people

Expert Q&A Tips Apply a topical anesthetic on the injection site so its less painful when you receive it.Thanks Warnings Contact a doctor or go to the emergency room if you experience nausea, vomiting, facial swelling, loss of vision, or a fever after an injection that shouldnt result in these symptoms.Thanks Always contact your doctor if you have questions about your medications or your post-injection symptoms get worse instead of better.Thanks References About This Article Reader Success Stories "Very helpful and knowledgeable article."

pylori) infection in your gastrointestinal tract Frequent use of antacids, protein pump inhibitors, or other acid blockers Crohns disease and celiac disease Patients over the age of 50 with a decrease in stomach acid Alcoholism Increased B12 Requirements: A MTHFR mutation in your genes Preservative-free Methyl B12 (Methylcobalamin) Injections It is estimated that up to 40% of the adult U.S