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Individuals receiving compounded formulations that include B6 may experience: Improved tolerability during dose escalation Reduced dropout rates Increased likelihood of staying with long-term therapy These potential benefits are still being explored in broader clinical settings, but they continue to gain attention through real-world provider feedback

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J Clin Endocrinol Metab 100:850859 Lafortuna CL, Minocci A, Capodaglio P, Gondoni LA, Sartorio A, Vismara L, Rizzo G, Grugni G (2014) Skeletal muscle characteristics and motor performance after 2-year growth hormone treatment in adults with PraderWilli syndrome