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and (3) the deltaSOFA defined as the difference between the worst SOFA score during the first 5 days of ICU stay and the SOFA score on admission

The half-life of NO and therefore its biological activity is decisively determined by oxygen-derived free radicals such as superoxide anions, 32 which as mentioned above rapidly bind to NO to form the highly reactive intermediate ONOO

Investigating whether arginine methylation is a universal mechanism utilized by other mosquito-borne viruses to facilitate viral replication would be an interesting avenue of research