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Gibco, United States) supplemented with 10% fetal bovine serum, 2 mM L-glutamine, 100 g/mL penicillin, and 100 g/mL streptomycin in a 37C incubator with 5% CO 2

21 However, 7% of individuals experienced worsening symptoms with selenium supplementation, indicating that while selenium was beneficial for a majority, it is not without risk for everyone

Peroxynitrite is highly toxic to neurons and causes hyper-excitability of the central nervous system, a process known as "kindling." This leads to autonomic nervous system dysfunction (dysautonomia), sensory overload, and severe cognitive deficits

Available online at: (Accessed August 25, 2025)