The most common side effects of tirzepatide include nausea (reported in 2030% of patients), diarrhea, vomiting, constipation, abdominal pain, and decreased appetite
Safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression: a systematic review and meta-analysis of randomised placebo-controlled trials
First-line approaches recommended by NICE and the NHS include: Dietary modification a balanced, calorie-reduced diet tailored to individual needs, with guidance from a registered dietitian where appropriate Increased physical activity at least 150 minutes of moderate-intensity aerobic activity per week for adults, in line with the UK Chief Medical Officers' physical activity guidelines Behavioural interventions cognitive behavioural therapy (CBT)-based programmes, group support, and self-monitoring strategies For individuals with a BMI of 30 kg/m or above (or 27.5 kg/m in certain ethnic groups), pharmacological treatment may be considered alongside lifestyle interventions, subject to clinical assessment and specific eligibility criteria: Orlistat reduces dietary fat absorption and is available via GP prescription
Compression Knee Sleeve For many, accelerated recovery and comfort are top priorities when managing knee injuries
