Diagnosing Hepatic Encephalopathy Utilizing Gut Microbiota Composition, Aumena Choudhry*, Michael Einhorn*, Maxwell Lee*, Meghana Malaya*, Akashdeep Randhawa*, Timur Oljuski**, Masoumeh Sikaroodi and Pat Gillevet *=primary author **=secondary author 37
SAM-e provides the methyl group in the production of essential biomolecules including: Acetyl-L-Carnitine: Neuronutrient and membrane-transporting agent Epinephrine & adrenaline: Endogenous catecholamfine, stress hormone and neurotransmitter Phosphatidylcholine: important component of biological membranes Carnitine: Transporter of fatty acids into mitochondria Phosphocreatine: ATP reservoir Melatonin: Circadian rhythm modulator Aminopropylation SAM-e also plays an important role in the synthesis of polyamines using the aminopropylation pathway
It is abundant in foods of animal origin, especially in beef liver, lams, oysters, fish and dairy products
A comprehensive evaluation with a healthcare provider will help ensure that glutathione IV therapy can be beneficial and safe