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Patients should: Weigh themselves once weekly at the same time and under consistent conditions Record measurements in a diary or app to identify trends Aim for gradual weight loss (NHS advises 0.51 kg per week is generally safe and sustainable) Understand that response to GLP-1 therapy varies between individuals Report unexpected rapid weight loss or gain to their healthcare provider It is important to recognise that weight loss may plateau after several months, and this does not necessarily indicate treatment failure

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Additionally, the drug label includes a boxed warning related to a potential risk of thyroid tumors

Due to the presence of different lengths of acyl chains and tautomers, there is a wide variety of acylcarnitines