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These can be listed as follows: Reduction of Oxidative Stress: Glutathione is a powerful antioxidant, and its application during IVF treatment may help reduce oxidative stress in the in vitro environment
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We also examined gene expression changes induced by C1-27 in HCT116 cells after 4 and 24 h treatment to observe the early and late response to GSTO1 inhibition, respectively (Supplementary Tables 1417 and 2023)
In contrast, no significant cytotoxicity was observed in the other cell lines showing that in chimera M8-03, the phenotype of MRP1-induced cell-death is linked to a single amino-acid substitution, D1228G
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