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Genetic polymorphisms in Keap1 or Nrf2 further influence individual susceptibility to HTN and response to therapy, highlighting the need for personalized approaches ( 6 Oxidative stress and diabetes mellitus OS in DM operates as both a causal driver and consequential amplifier of disease progression, accelerating metabolic dysfunction and tissue damage in a similar way as in HTN (Papaetis et al., 2025)

My mum said she thinks its just a normal reaction but I just wanted to see if anyone else has ever had this heavy, achy pain in the upper arm going into the armpit and shoulder