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Summary of preclinical works Pretreatment with nicotinamide mononucleotide, an NAD precursor derived from niacin, in rats exposed to HS results in a decrease in interleukin 6 (IL-6) and venous lactates, and in the preservation of mitochondrial respiration assessed by high-resolution respirometry

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These patients mostly received chronic low-frequency (10 Hz) cerebellar stimulation alternating between the left- and right-side, which markedly reduced the frequency of seizures for up to 3 years [111]

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