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[206] observed no significant change in ferroptosis hallmarks (ACSL4, GPX4, iron, and malondialdehyde) during severe myocardial ischemia

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As discussed in our previous review (Reference Ashoori and Saedisomeolia12) , in some cases, riboflavin has led to a decrease in oxidative stress, while the activity of antioxidant enzymes has not increased concurrently, a finding that has been reported in recent studies as well (Reference Btn, Nazrolu and Demirci24)