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In PIONEER 4, oral semaglutide 14 mg once daily was compared with both liraglutide 1.8 mg and placebo in patients receiving metformin with or without a sodium-glucose cotransporter-2 inhibitor (SGLT2i) [8]

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Patients who are actively losing weight often choose XERF treatments to help: Improve skin laxity after weight loss Stimulate natural collagen production Enhance skin firmness and elasticity Create a more sculpted and contoured appearance Support lifting and tightening of areas such as the face, neck, abdomen, arms, and body Improve overall skin quality and texture By combining Retatrutide with XERF, patients can address both weight loss and skin quality concerns simultaneously, helping them achieve a more complete transformation