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Consequently, the British Thoracic Society and the European Respiratory Society recommend in their guidelines that long-term inhaled antibiotic treatment should be considered for patients with chronic Pseudomonas aeruginosa infections who experience three or more exacerbations per year (83, 84)

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If excess free copper were present in a poorly manufactured preparation, it could generate hydroxyl radicals via Fenton-type chemistry and produce artifactual oxidative stress in cell cultures