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Exploiting the genetic diversity of maize using a combined metabolomic, enzyme activity profiling, and metabolic modeling approach to link leaf physiology to kernel yield

In summary, CPP-CAND is a FOXO4-p53 interaction inhibitor that is anticipated to offer cost-effectiveness, high selectivity, and safety compared to previously developed peptide interaction inhibitors

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Inheritance of the Peg11/RTL1 KO allele from father causes late fetal lethality due to late fetal growth retardation, whereas maternal transmission leads to overexpression of Peg11/Rtl1 and neonatal lethality (196, 197)