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Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice

In women with polycystic ovary syndrome (PCOS) and obesity, GLP-1 therapy has shown promise in improving reproductive hormone profiles, though this represents an off-label use with limited evidence

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The Ang IV analogue peptide 4 and the Nle-Ang IV analogue 5 provide examples comprising two basic amino groups accessible for protonation in the N-terminal of the peptides and flanking hydrophobic 2-isopropyl and n-butyl side chains, respectively (Figure 2) (Sardinia et al., 1994)