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257 WangY.ChenC.HuangW.HuangM.WangJ.ChenX.et al (2019c)
Previous study has shown that SGLT-2 inhibitors can up-regulate SIRT1 in renal tubules (166), thereby positively regulating autophagy and improving proteinuria (167)
Notably, while total FOXO4 protein levels remained consistent between young and elderly men, a striking age-dependent shift in its subcellular localization was observed: FOXO4 predominantly resided in the cytoplasm in young Leydig cells but translocated to the nucleus in aged cells
Research into the effects of glutathione supplementation on cancer treatment outcomes is ongoing, with mixed results
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