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They identified, on average, higher levels of MDA and lower levels of GSH and FRAP in cases compared to controls, all of which align with a higher prooxidant and lower antioxidant profile within cases of PHG

530 Autophagy induction and immune rebalancing In contrast, autophagy induction can be therapeutically beneficial when autoimmune pathology is driven by defective clearance programs, immune-complex burden, or mitochondrial damage