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2 Department of Biological Science, Purdue University, West Lafayette, IN, USA *These authors contributed equally to this work Abstract: Glutathione S-transferase (GST) is a Phase II metabolic enzyme that is an important facilitator of cellular detoxification

As mentioned above, abnormally accumulated proteins on the mitochondrial surface and in the TOM channel are eliminated, while proteins within the matrix are processed via the UPR mt pathway (Fig