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Cell types were annotated based on known immune cell marker genes, including: CD4+ T cells (CD2, CD4, CCR7, CD3D), CD8+ T cells (CD8A, GNLY, GZMB), NK cells (LTB, NKG7), plasma cells (XBP1, CD27), B cells (MS4A1, CD79A), and monocytes (CD14, LYZ, FCGR3A)

In this study, Clementi et al observed higher eryptosis levels in patients with advanced CKD (stage G4 and stage G5), compared with early stages of chronic renal damage (stage G1, G2, and G3) [260]