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XO appears in the early stage of skin inflammation caused by lipopolysaccharides (LPS, a strong stimulator of toll-like receptors) (39)

Neurogenesis and new neuron formation For most of the twentieth century, neuroscience held a core belief: the adult brain does not produce new neurons

Several neurotransmitters (serotonin, noradrenaline, dopamine, and histamine), peptides (neuromedin U, urocortin, bombesin, amylin, galanin), hormones (thyroid hormone, growth hormone) and cytokines (ciliary neurotrophic factor) also play a role in modulating feeding behavior and energy expenditure [5-10]

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