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The tissue was finely minced using scissors and then digested in KRPH buffer (20 mM HEPES,5 mM KH2PO4,1 mM MgSO4.7H2),1mMCaCl2.2H2O,136 mM NaCl,4.7 mM KCL supplemented with 1 mg/ml collagenase A (Sigma-Aldrich) for 1 h at 37 C with gentle agitation

Optionally, a controlled-release formulation includes otoprotective agents, such as antioxidants, alpha lipoic acid, calcium, fosfomycin or iron chelators, to counteract potential ototoxic effects that may arise from the use of specific therapeutic agents or excipients, diluents, or carriers

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Treatment: Lichen planus doesnt have a cure, but some treatments can make you feel more comfortable and speed up the healing process