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Wu F, Jacobs DR Jr, Daniels SR, et al
It focused on individual-level randomized clinical trial (RCT) data of GLP1-RA from the HARMONY program [Liraglutide (389 individuals) and Albiglutide (1,682 individuals)], the PRIBA study [Liraglutide (397 individuals), exenatide (223 individuals), and Tayside & Fife (415 individuals)
The authors evaluated whether a standardized intraoperative bundle combining intraparotid botulinum toxin A (BTX-A) and bovine collagen membrane interposition is associated with fewer complications than standard enucleation alone
However, the effect of peptide polyagonists needs further exploration in animal studies as well as in mechanistic studies to investigate the potentially additive or synergistic effect of different receptor agonists, and their specific mechanisms of action
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