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As we age, tendons stiffen, gut barrier function deteriorates, wound healing slows, and chronic low-grade inflammation ("inflammaging") erodes organ function

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

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In addition, levocarnitine buffers excess intramitochondrial acyl-CoA, regenerating free coenzyme A and potentially preventing inhibition of critical metabolic enzymes