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Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

These discoveries have given rise to the idea that bipolar disorder is a bioenergetic and metabolic disease with psychiatric manifestations, and that disruptions in the molecular and cellular signalling networks that regulate brain energy metabolism in a biphasic manner are a primary, sufficient cause of bipolar disorder-related phenomena [189]

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If trials continue to go well, experts estimate: FDA submission: 2026 Possible approval: late 20262027 Thats best-case, not guaranteed