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Additionally, in the SELECT trial, adults with obesity and without diabetes receiving semaglutide had a 20% lower risk for major adverse CV events compared with placebo (HR = 0.8

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Whether it works for a specific individual depends on the undisclosed formula, transdermal absorption efficiency, individual physiology, and lifestyle

A study available on PubMed Central explores this connection, highlighting how the gut microbiomes composition can influence GLP-1 secretion and overall metabolic health