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For patients with metabolic disease, obesity-related comorbidities, or complex medical histories, these uncertainties create unacceptable safety concerns

Del Tredici and Braak, 2020)

GLP-1 receptor agonists the class of drugs that includes Ozempic, Wegovy, and Mounjaro have rapidly moved from niche diabetes treatments to a mainstream cultural phenomenon

At the end of 80 weeks, participants on each dose lost the following amount of weight on average: 4 mg: 19% or around 47 lbs 9 mg: 25.9% or about 64 lbs 12 mg: 28.3% or around 70 lbs These numbers compare to participants who received a placebo and lost an average of 2.2%, or about 5.5 lbs