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7 and 8) revealed severe neuronal degeneration in MSG-exposed rats and elevated tau protein deposition, demonstrating the neurotoxic effects of MSG exposure in early life, resulting in widespread neural cell death and tauopathy, which are key components of many neurodegenerative diseases, including AD 78,79

To validate our findings, we used atp-3 RNAi, a positive control, which is known to cause mitochondrial fragmentation due to ATP synthase dysfunction 85,86

By activating PPAR (peroxisome proliferator-activated receptor ) and modulating CPT1A expression, BNP could reduce hepatic lipogenesis and fibrosis [117]

Further reading Davis, M., et al