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CagriSema appears closest to a possible approval given its reported regulatory submission, while retatrutide leads on reported efficacy
The symptoms are caused by an exaggerated spillover of bile acids from the small intestine to the large intestine due to increased bile acid synthesis in the liver and/or decreased reabsorption of bile acids in the small intestine
Choosing which GLP-1 receptor agonist is easiest on the stomach is a common concern for patients starting these medications for type 2 diabetes or weight management
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