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10.1016/j.ijwd.2021.07.00 Petit A: Skin lightening and its motives: a historical overview

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Claims about human outcomes are extrapolated from animal models without pharmacokinetic or clinical validation

[49] further noted that GLP1R is widely expressed in retinal endothelial cells, and its activation significantly inhibits the expression and secretion of multiple inflammatory factors such as TNF- and IL1, reducing immune cell infiltration