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Rapid depletion of endogenous UA reserves during severe ischemia leads to the failure of the natural antioxidant defense system, triggering the need for urgent exogenous UA supplementation for cerebral protection during acute stroke [150]
It's like capsaicin, but the phenyl group added really helps enhance bioavailability
Date: August 17, 2015 Event: 250th American Chemical Society National Meeting & Exposition Location: Boston, MA Alexis N Newton Electrophilic sesquiterpene lactones modulate the heat shock response system
doi: 10.3389/fphys.2018.00113 [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Yu FF, Yuan Y, Ao Y, et al
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