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Abbreviations AgRP: Agouti-related protein MSH: Alpha melanocyte-stimulating hormone ARC: Arcuate nucleus CART: Cocaine- and amphetamine-regulated transcript CCK: Cholecystokinin CFA: Conjugated fatty acids EECs: Enteroendocrine cells FFARs: Free fatty acid receptors GLP-1: Glucagon-like peptide-1 NPY: Neuropeptide Y NT: Neurotransmitters NTS: Nucleus tractus solitarius POMC: Proopiomelanocortin PYY: Peptide YY SCFAs: Short-chain fatty acids References Deehan EC, Mocanu V, Madsen KL

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The immune system becomes dysregulated and begins attacking self-tissue like it's a foreign invader, causing increased inflammation and tissue damage