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They work by creating microthermal zones of controlled thermal injury that result in dermal remodeling and tightening, and theyre a mainstream approach for patients with moderate to severe photoaging and crepey skin, she said

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While rhabdomyolysis has previously been reported after several months of tirzepatide therapy, the present case is notable for the onset of this adverse effect following a single supratherapeutic dose ( In conclusion, the underlying pathophysiological mechanism remains uncertain

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