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While all treatments raised DNA fragmentation in controldiet animals, they effectively reduced fragmentation in AGEdiet animals, returning it to control levels (Fig

Net DA release and net rCBF change DA release was calculated by subtracting the D 2/3 R BPnd in the drug condition (e.g., NAL) from that in the SAL condition and dividing the result by D 2/3 R BPnd in the SAL condition (to normalize for regional differences in D 2/3 R)

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