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Effects of Tesamorelin on Non-Alcoholic Fatty Liver Disease in HIV: A Randomised, Double-Blind, Multicentre Trial

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Microdosing involves using substantially lower doses than standard therapeutic regimens, falling outside approved prescribing guidance

CPA digestion of albumin To initiate in vitro enzymatic cleavage by CPA, unfused albumin (WT or QMP) or albumin fused to GLP-1, FIX 9 , or ACE2 13 (15 M), in DPBS (pH 7.4) (Sigma-Aldrich), were incubated with 30 g/mL of human pancreatic CPA (Elastin Products Company, Inc.) for 5 h at 37 C on a shaker platform set to 450 RPM