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Exploratory analyses revealed exenatide significantly reduced heavy drinking days and total alcohol intake in a subgroup of obese patients. Senior author Professor Anders Fink-Jensen told medscape.com: Something is happening in the brain, and activation of the reward centre is hampered by the GLP-1 compound. And he noted: If patients with AUD already fulfill the criteria for semaglutide (or other GLP-1 analogs) by having type 2 diabetes and/or a Body Mass Index (BMI) over 30kg/m2, they can of course use the compound right now. Professor Fink-Jensens team is also beginning a study in patients with AUD and a BMI greater than 30 kg/m2 to investigate the effects on alcohol intake of semaglutide up to 2.4 mg weekly (the maximum dose currently approved for obesity patients in the US)

13, Apr

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