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Nevertheless, the use of APAP in babies and young children, which was a relatively uncommon occurrence half a century ago, is now extremely common.One potential argument that APAP cannot cause ASD is that the rising rates of ASD over time are, at least in part, a consequence of changing diagnostic criteria, increased awareness, and other factors (discussed by co-author CDN and colleagues [35])

The association between the dysregulation of the inflammatory response and the pathophysiology of ADHD is possible as a result of the role of inflammation in neurogenesis, differentiation, and neuronal function [30,35,36,37]

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