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After cyclization, the peptide-resin was washed and the peptide was cleaved from the resin and any remaining protecting groups using trifluoroacetic acid (TFA) in the presence of water and 1,2-ethanedithiol (EDT)

10.1016/j.bbrc.2017.09.108 96 SuthaharN.MeijersW

Key results from Calocurb's fourth human clinical study include the following: Calocurb is clinically shown to improve body composition by reducing body fat without losing muscle mass Average weight loss of 8.3 lbs (3.77 kg) after six months, compared to 0.88 lbs (0.4 kg) with the placebo group Over 6.5x greater reduction in body fat vs placebo Average body fat loss of 9.9 lbs (4.49 kg) vs 1.5 lbs (0.68 kg) after six months of consistent use of Calocurb vs placebo 3.5x greater reduction in visceral fat vs placebo Average visceral fat loss of 5 in2 (32.5 cm2) vs 1.4 in2 (9.1 cm2) lost after six months of consistent use of Calocurb vs placebo For over a decade, Calocurb has undertaken ground-breaking clinical research into Amarasate to continue bringing natural weight management solutions to those interested in GLP-1 and weight loss options.